SNS GlycoPhase | Glucose Disposal Agent | 120 Veggie Capsules | UK

GlycoPhase is a comprehensive, nine-ingredient Glucose Disposal Agent (GDA) formulated by Serious Nutrition Solutions to support healthy glucose metabolism, insulin sensitivity, and nutrient partitioning. Combining research-backed ingredients including Berberine HCI, Agmatine Sulfate, Alpha Lipoic Acid, Na-R-ALA, Saffron, and BioPerine®, GlycoPhase is designed to help the body make more efficient use of carbohydrates — supporting lean muscle, dramatic pumps, and a favourable body composition environment. Available at Evolution Supplements UK.

What is a Glucose Disposal Agent (GDA)?

Glucose Disposal Agents are a class of supplements designed to enhance nutrient uptake into cells by increasing insulin sensitivity and improving the efficiency of the body's natural insulin response. The goal of an effective GDA is to support more stable glucose levels, promote glucose uptake into muscle cells rather than fat cells, and help the body make better use of carbohydrates and body fat as fuel sources. The result, when combined with diet and training, is a leaner, fuller, more muscular physique.

Key Features

• 9 research-backed ingredients in a single comprehensive formula
• Supports healthy glucose metabolism and insulin sensitivity
• Promotes nutrient partitioning — directing carbohydrates towards muscle cells
• Dramatic muscle pumps from increased glucose uptake in skeletal muscle
• BioPerine® included for enhanced absorption of all ingredients
• 30 servings per container — 4 veggie capsules per serving
• Vegetarian-friendly veggie capsule shell

Nutritional Information

Serving Size: 4 Veggie Capsules  |  Servings Per Container: 30

** Percent Daily Value not established. % DV based on a 2,000 calorie diet.

Other Ingredients: Vegetable Cellulose (capsule), Magnesium Stearate, DiCalcium Phosphate, Titanium Dioxide.

Ingredient Breakdown

Agmatine Sulfate (1,000mg)

Agmatine Sulfate is one of the few ingredients demonstrated to increase GLUT-4 transportation and mRNA expression in skeletal muscle — helping to ensure that glucose transport is directed towards muscle cells rather than fat cells. It achieves this through an indirect action on beta-endorphin secretion which, similarly to exercise, promotes GLUT-4 translocation into skeletal muscle via activation of imidazoline I2A receptors.

Berberine HCI (500mg)

Berberine HCI is widely regarded as one of the most effective ingredients for supporting healthy blood glucose levels. Its primary mechanism involves activation of AMPK, which promotes glycogen synthesis and increases glucose uptake in insulin-sensitive cells — removing glucose from the blood more rapidly for immediate use or glycogen storage. AMPK activation also supports insulin sensitivity through pathways independent of insulin itself, making Berberine particularly effective in challenging metabolic environments.

Bitter Melon Extract 10:1 (500mg)

Bitter Melon contains three key active constituents — charantin, vicine, and polypeptide-p — each of which promotes glucose clearance from the blood via distinct physiological mechanisms. These range from stimulation of skeletal muscle glucose utilisation to preservation of islet B cells, which are integral to normal insulin production and function. Bitter Melon also helps protect islet B cell health by downregulating the cytokines responsible for cell degradation.

Banaba Leaf Extract (300mg, Std. to 2% Corsolic Acid)

Banaba Leaf's primary active compound, Corsolic Acid, has been shown in human studies to decrease blood glucose within 60 minutes through its ability to increase cellular uptake of glucose. Its proposed mechanism involves stimulation of GLUT-4 translocation and insulin receptor phosphorylation — both of which promote efficient glucose clearance from the blood. In research combining Banaba with other GDA ingredients, meaningful reductions in body weight were observed over a 12-week period.

Gymnema Sylvestre Extract (300mg, Std. to 25% Gymnemic Acids)

Gymnemic Acids have a similar molecular structure to glucose, allowing them to compete for the same intestinal receptor sites and effectively delay the absorption of glucose into the bloodstream — helping to prevent excessive insulin secretion that could otherwise result in glucose being stored in adipose tissue. Gymnema may also help reduce sugar cravings by occupying taste receptors on the tongue. Additional proposed mechanisms include increasing insulin secretion, promoting islet cell regeneration, and improving glucose utilisation.

Alpha Lipoic Acid (150mg)

Alpha Lipoic Acid (ALA) is a mitochondrial compound with a broad range of metabolic functions. In the context of GlycoPhase, ALA supports glucose uptake and AMPK activation — mechanisms closely aligned with those of Berberine. Research has shown ALA can significantly influence gene expression of key enzymes involved in glucose metabolism, increasing the rate of glycogen synthesis in the liver and supporting more efficient carbohydrate utilisation.

Na-R-Alpha Lipoic Acid (100mg)

Na-R-ALA is the sodium salt of the R-isomer of Alpha Lipoic Acid — the most stable and bioavailable form of ALA currently available. It operates through the same mechanisms as standard ALA but with significantly greater potency and absorption. Na-R-ALA is particularly noted for its ability to produce dramatic muscle pumps resulting from enhanced glucose uptake in skeletal muscle.

Saffron — Crocus Sativus (30mg)

Saffron is one of the most underutilised GDA ingredients available. It increases insulin sensitivity through both insulin-dependent and non-insulin-dependent pathways, and plays a significant role in promoting GLUT-4 transport via AMPK activation. Saffron activates both the AMPK and PI 3-Kinase/Akt pathways — two distinct routes that regulate glucose transport into skeletal muscle — making it highly effective at supporting glucose clearance into muscle tissue and favouring glycogen storage over adipose tissue storage.

Chromium (300mcg, as Chromium Nicotinate Glycinate Chelate)

Chromium is an essential mineral that plays an important role in supporting the body's normal insulin response and healthy glucose metabolism. Chromium in its chelated nicotinate glycinate form represents one of the most bioavailable versions available, offering superior absorption compared to basic chromium picolinate. Chromium supplementation may also support healthy eating habits by helping to reduce snacking behaviour.

BioPerine® (10mg, Std. to 95% Piperine)

BioPerine® is a patented black pepper extract standardised to a minimum of 95% piperine, included to significantly enhance the bioavailability and absorption of all other ingredients in the GlycoPhase formula — ensuring maximum efficacy from every capsule.

How to Use SNS GlycoPhase

Take 4 veggie capsules as a serving, 30 minutes before a carbohydrate-containing meal. Use consistently as part of a balanced diet and training programme. Do not exceed the recommended daily intake.

Who Is GlycoPhase For?

• Athletes and bodybuilders looking to optimise carbohydrate utilisation and nutrient partitioning
• Anyone seeking a comprehensive, multi-ingredient GDA formula
• Gym-goers wanting to support dramatic muscle pumps through enhanced glucose uptake
• Those on higher-carbohydrate diets wanting to support healthy glucose metabolism

Frequently Asked Questions

What makes GlycoPhase different from other GDA supplements?

Many GDA products simply block carbohydrate absorption in the intestine without actively supporting glucose transport into muscle cells. GlycoPhase combines nine specifically selected ingredients that work across multiple pathways — including GLUT-4 translocation, AMPK activation, and PI 3-Kinase signalling — to support genuine glucose uptake into skeletal muscle rather than just limiting absorption.

When should I take GlycoPhase?

GlycoPhase is best taken approximately 30 minutes before a carbohydrate-containing meal to support healthy glucose metabolism during and after eating.

Is GlycoPhase suitable for vegetarians?

Yes. GlycoPhase uses a vegetable cellulose capsule shell, making it suitable for vegetarians.

Can I stack GlycoPhase with other supplements?

Yes. GlycoPhase stacks well with protein powders, creatine, and pre-workout supplements. If you are taking any medications or have an existing health condition — particularly relating to blood glucose management — always consult your GP before use.

Why Buy from Evolution Supplements?

At Evolution Supplements, we stock only genuine, quality-assured products from trusted brands. Order SNS GlycoPhase from us for authentic products, fast UK dispatch, competitive pricing, and dedicated customer support.

Food supplement. Always read the label before use. Do not exceed the recommended daily intake. Keep out of reach of children. Store in a cool, dry place. Consult your GP or healthcare professional before use if you are pregnant, breastfeeding, taking any medication, or have any known or suspected medical condition — particularly if you are managing blood glucose levels or taking diabetes-related medication.